SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. ("Biosplice"), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA splicing for . Samumed adopted a fresh operating philosophy from the beginning one based on a goal of building a broad technology platform aimed at modulating regenerative pathways to improve patient health. Equity securities are offered through EquityZen Securities. Invest better with The Motley Fool. Biosplice Therapeutics (formerly Samumed) "Biosplice's mission is to restore health by delivering first-in-class therapies that harness alternative splicing.". Merck has been looking to get its blockbuster drug Keytruda into earlier lines of treatment, and one of its latest trial results has the anti-PD-1 antibody moving firmly in that direction. As chief business officer and strategy chief for the Broad over a decade-long stretch, hed worked with all the big names in a scientific discipline that promises to upend the therapeutics field eventually. Stemming from foundational discoveries in Wnt pathway modulation, Biosplice has elucidated novel biology linking CLK/DYRK kinases to the therapeutic regulation of alternative splicing. AT-GAA consists of biologic cipaglucosidase alfaand miglustat, a stabilizer of the biologic. Chairman Per Wold-Olsen was also voted out, effective immediately. SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. ("Biosplice"), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA splicing for major diseases, announced today it has closed $120 million in equity financing from a new biotechnology investment syndicate. This week began with four biopharma companies announcing intentions to become publicly traded companies and its ending with three companies making their debut on the Nasdaq. La Jolla, California, United States 101-250 Post-IPO Equity Public www.fatetherapeutics.com 3,290 Highlights Stock Symbol NASDAQ:FATE Acquisitions 1 Total Funding Amount $1.2B Contacts 80 Employee Profiles 21 They have a separate drug for autoimmune disease and for oncology that are partnered with Bristol Myers Squibb. It's already testing its drug called CAN-2409 in prostate cancer, and then it's planning phase 3 for brain cancer next year. Biosplice's drugs in clinical development include lorecivivint for osteoarthritis (in Phase 3), cirtuvivint for numerous cancers, and a broad pipeline that ranges from Alzheimer's disease to. The Motley Fool has a disclosure policy. Initial public offerings (IPOs) can provide opportunities for investors to jump aboard promising stocks early. Biosplices target class governs the selection of tissue-specific mRNA splice sites, making them attractive, druggable targets within the cellular command and control center. The biotech boom in the early days of the pandemic helped fuel the rise of Taysha Gene Therapies and Jaguar Gene Therapy, but the winter freeze that followed has also caused a hunkering down for the biotechs, chaired by ex-AveXis CEO Sean Nolan. In this case, Keytruda was being used as a treatment both before and after surgery. Investing in private companies may be considered highly speculative and involves high risks including the risk of losing some, or all, of your investment amount. The malignant cells permeated his bones, kidney, lungs and liver, and in December, his oncologist told him there was no point in continuing chemotherapy treatment. The company started in 2015 and is . CRISPR is a pair of biological scissors that can cut and replace genes in cells and living organisms which can open up the potential to cure genetic diseases and perform DNA-based diagnostics. That level of fanfare was nowhere to be found on Thursday, when. And it highlighted how leaders are driving forward not only science and drug development, but also inclusion and the diversity needed to ensure medicines benefit everyone. Biosplice Therapeutics, Inc. All rights reserved. 329 followers 290 connections. S AN DIEGO Biosplice, once the world's most valuable biotech startup, is laying off nearly a quarter of its workforce and has stopped internal development of one of its late-stage medicines, a. Learn More. Biosplice has over 80 publications in journals and as conference presentations. At least those big pharma partners have looked at the early-stage preclinical data. EquityZen Securities LLC (EquityZen Securities) is a subsidiary of EquityZen Inc. EquityZen Securities is a broker/dealer registered with the Securities Exchange Commission and is a FINRA/SIPC member firm. In addition to the three companies above, Salt Lake City-based Recursion Pharmaceuticals, Netherlands-based LAVA Therapeutics, New Jersey-based Certara, and San Diego-based Evofem are all lining up to begin trading as a public company. By accessing this site and any pages thereof, you agree to be bound by our Terms of Use.EquityZen and logo are trademarks of EquityZen Inc. Other trademarks are property of their respective owners. 2023 EquityZen Inc. All rights reserved. Powered by Madgex Job Board Software, four biopharma companies announcing intentions, expects to raise approximately $240 million, $125 million in a Series B financing round, $120 million in a Series B financing round. 1985 - 2023 BioSpace.com. Biosplice Therapeutics, Inc. SAN DIEGO, April 15, 2021 (GLOBE NEWSWIRE) -- Biosplice Therapeutics, Inc. (Biosplice), a clinical-stage biotechnology company pioneering therapeutics based on alternative pre-mRNA splicing for major diseases, announced today it has closed $120 million in equity financing from a new biotechnology investment syndicate. These kinases govern the selection of tissue-specific and disease-selective RNA splice-sites, defining them as druggable targets within the command and control center of proteome diversification. Learn more about Biosplice Therapeutics stock Updated on: Jun 12, 2022 Register for Details Anytime we're talking about extended survival, that's the gold standard for cancer. In this Motley Fool Live video recorded on June 30, 2021, Motley Fool contributors Keith Speights and Brian Orelli discuss two upcoming biotech stock IPOs you'll want to have on your radar. *Average returns of all recommendations since inception. The company manufactures an anti-osteoporosis drug called Lorecivivint, which was going through phase 3 clinical trials as of summer 2021. Viking accuses Chinese biotech of 'ruse' to raid trade secrets and make off with NASH cache. For more details on financing and valuation for Biosplice Therapeutics, register or login. We are delighted to align with our new investors and board behind the immense therapeutic potential of Biosplice, said Cevdet Samikoglu, Chief Executive Officer of Biosplice. Biosplice Therapeutics's latest funding round was a Series B for $120M on April 15, 2021. The data in the chart above is based on data derived from our proprietary XP calculation model and may be changed, adjusted and updated without prior notice. Total amount raised across all funding rounds, Total number of Crunchbase contacts associated with this organization, Total number of employee profiles an organization has on Crunchbase, Total number of investment firms and individual investors, Total number of organizations similar to the given organization, Descriptive keyword for an Organization (e.g. That's in the same pathway as JAK, which we've talked about a lot. Design said it expects to raise approximately $240 million from the IPO, a little bit higher than the $228 million the company previously anticipated. Please note the magic link is Seed, Series A, Private Equity), Alternate or previous names for the organization, Tags are labels assigned to organizations, which identify their belonging to a group with that shared label, Whether an Organization is for profit or non-profit, General contact email for the organization. Chief Operating Officer. Learn more about how Forge might help you buy pre-IPO shares or sell pre-IPO shares. This morning, two of those companies, Ikena Oncology andDesign Therapeutics, join Edgewise Therapeutics by trading on the exchange. Biosplice's drugs in clinical development include lorecivivint for osteoarthritis (in Phase 3), cirtuvivint for numerous cancers, and a broad pipeline that ranges from Alzheimer's disease to. Making the world smarter, happier, and richer. Vividion Therapeutics has filed to go public. From delivering prescriptions to coordinating with insurance, digging for discounts, and answering, Alto works behind-the-scenes to remove any obstacles standing in the way of your care. Michael White, Ph.D. joins Samumed as Chief Scientific Officer, Samumed Taps Pfizers Michael White as Its Chief Scientific Officer, Samumed Publishes Unique Mechanism of Action for SM08502 in Targeting Gastrointestinal Tumors, Samumed Announces Publication of Preclinical Data Demonstrating That SM07883 is a Potential Treatment for Alzheimers Disease, Samumed Launches Phase 3 Lorecivivint (SM04690) Clinical Program in Knee Osteoarthritis, Samumed Announces Positive End-of-Phase 2 Meeting with FDA for SM04690 in Knee Osteoarthritis. Register today to connect with our Private Market Specialists and learn more about new pre-IPO investment opportunities. Maybe the next best thing is to have big pharma partners endorsing its drugs. Intriguing companies here run the gamut from Biosplice Therapeutics, which is working on tissue-level regeneration, Pipeline Therapeutics, focused on regenerative therapies for neurological disease, and LyGenesis, an organ regeneration company. 308 followers 310 connections. Investors in this latest round comprise Eventide Asset Management, aMoon, SymBiosis II, Sands Capital, Verition Fund Management and others, and also includes existing investor support. Out of these 85 have been granted leading to a grant rate of 98.8%. Get stock recommendations, portfolio guidance, and more from The Motley Fool's premium services. The stock will open this morning at $20 per share, which is on the upper end of what the company projected. Edgewises lead drug candidate is EDG-5506, an orally administered small molecule designed to address the root cause of dystrophinopathies, in development for the treatment of Becker muscular dystrophy (BMD) and Duchenne muscular dystrophy (DMD). Ikena plans to file an IND in the second half of 2021 and to first initiate a Phase Iclinical trial first evaluating single-agent IK-930 in biomarker-enriched patient populations, such as those with Hippo pathway-altered tumors. Biosplice's mission is to restore health by delivering first-in-class therapies that harness alternative splicing. Investors must be able to afford the loss of their entire investment. Biosplices target class governs the selection of tissue-specific mRNA splice sites, making them attractive, druggable targets within the cellular command and control center. Therapeutics, register or login Lorecivivint, which we 've talked about a lot restore by... The next best thing is to have big pharma partners endorsing its drugs the smarter! Linking CLK/DYRK kinases to the therapeutic regulation of alternative splicing, register or login cancer next year the Motley 's., portfolio guidance, and more from the Motley Fool 's premium.! 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